Outcome of Intratympanic Gentamicin Injection for Ménière Disease

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منابع مشابه

Management of intractable Ménière's disease after intratympanic injection of gentamicin.

OBJECTIVES/HYPOTHESIS 1) To evaluate the efficacy of, and problems with, intratympanic gentamicin injection (ITG) in medically intractable definite Ménière's disease (MD) and secondary endolymphatic hydrops (EH); and 2) to review the vestibular status and treatment options of intractable vertigo even after ITG. STUDY DESIGN Retrospective case review and survey. METHODS 780 patients with def...

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Intratympanic gentamicin for Ménière's disease or syndrome.

BACKGROUND Ménière's disease is characterised by three major symptoms: vertigo, deafness and tinnitus, which may be accompanied by aural fullness, all of which are discontinuous and variable in intensity. While discontinuous, these symptoms are synchronous. Intratympanic application of gentamicin, an ototoxic aminoglycoside, is a relatively new ablative treatment for vertigo in Ménière's diseas...

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Intratympanic application of gentamicin for treatment of Menière's disease.

Since 1974 we have treated 118 patients suffering from unilateral and bilateral (two patients) Morbus Meniere with intratympanal applications of gentamicin-sulfate. In contrast to earlier attempts using this method, we did not try to destroy the vestibular apparatus, but taking into our considerations the recent findings about the pathophysiological mechanism of Morbus Meniere, only to damage t...

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one-shot, low-dosage intratympanic gentamicin for ménière's disease: clinical, posturographic and vestibular test findings.

background: ménière’s disease  has been  remained  as a difficult therapeutic  challenge. the  present  study aimed to   determine    the effects of  one-shot low-dosage intratympanic   gentamicin   on  vertigo control, auditory outcomes  and  findings of computerized  dynamic posturography  and   vestibular  evoked  myogenic potentials in patients with unilateral ménière’s disease. methods: in...

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Results of electrocochleography in Ménière's disease after successful vertigo control by single intratympanic gentamicin injection.

In the last several years, a promising new approach has been suggested in the therapy of Ménière's disease (MD): the low-dose intratympanic gentamicin therapy. By titrating the desired vestibular inhibition by single injections and infrequent administration, side effects concerning hearing can be held on an acceptably low level, while disease-related symptoms are often successfully eliminated. ...

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ژورنال

عنوان ژورنال: Otolaryngology–Head and Neck Surgery

سال: 2011

ISSN: 0194-5998,1097-6817

DOI: 10.1177/0194599811416318a183